Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320745 | 0.81 | CYP3A4 (0.45) | SIGMAR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL928913 | 0.73 | CYP3A4 (0.51) | SIGMAR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3228019 | 0.71 | CYP3A4 (0.49) | SIGMAR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13537596 | 0.71 | CYP3A4 (0.49) | SIGMAR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31254224 | 0.71 | CYP3A4 (0.49) | SIGMAR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL18428269 | 0.70 | CYP3A4 (0.50) | SIGMAR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14801490 | 0.68 | KMT2A (0.37) | SIGMAR1CYP2D6L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL14801489 | 0.68 | KMT2A (0.37) | SIGMAR1CYP2D6L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL14801488 | 0.68 | KMT2A (0.37) | SIGMAR1CYP2D6L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL7378791 | 0.68 | ALDH1A1 (0.40) | SIGMAR1CYP3A4CYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | claimed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | claimed |
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |