Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BCL9 | O00512 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957573 | 1.00 | CYP1A2 (0.39) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| SCHEMBL7955684 | 0.94 | HPSE (0.42) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| SCHEMBL7955687 | 0.94 | HPSE (0.42) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| SCHEMBL7959236 | 0.89 | CYP1A2 (0.49) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| SCHEMBL7959233 | 0.89 | CYP1A2 (0.49) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| SCHEMBL7962254 | 0.89 | MAPT (0.40) | ALDH1A1MAPTBCL9CTNNB1NT5E | |
| SCHEMBL7962256 | 0.89 | MAPT (0.40) | ALDH1A1MAPTBCL9CTNNB1NT5E | |
| SCHEMBL7957578 | 0.88 | MAPT (0.39) | ALDH1A1HPSEMAPTBCL9CTNNB1 | |
| SCHEMBL7948101 | 0.83 | CYP1A2 (0.53) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| SCHEMBL7948106 | 0.83 | CYP1A2 (0.53) | CYP1A2NFKB1THPOALDH1A1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819135-B1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1999-11-17 | — | — | EP | disclosed |