Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3201307 | 0.98 | KMT2A (0.36) | KMT2AESR1ESR2TDP1TP53 | |
| SCHEMBL8319298 | 0.97 | KMT2A (0.35) | KMT2AESR1ESR2TDP1TP53 | |
| SCHEMBL509923 | 0.85 | MEN1 (0.39) | KMT2AESR1ESR2TDP1TP53 | |
| SCHEMBL6829398 | 0.81 | SMN1; SMN2 (0.40) | KMT2ALMNAMEN1ALDH1A1HPGD | |
| SCHEMBL1866333 | 0.80 | HTT (0.42) | KMT2AMEN1ALDH1A1HPGDHTT | |
| Potassium SCHEMBL5102369 | 0.78 | HTT (0.41) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL5102368 | 0.78 | HTT (0.41) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL20723077 | 0.77 | ALDH1A1 (0.43) | KMT2AESR1LMNAMEN1ALDH1A1 | |
| SCHEMBL5791824 | 0.75 | MAPT (0.40) | KMT2ATDP1LMNAMEN1ALDH1A1 | |
| SCHEMBL2866226 | 0.74 | ESR1 (0.46) | KMT2AESR1ESR2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915880-A1 | AZOLO TRIAZINES AND PYRIMIDINES | Du Pont Pharmaceuticals Company (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003510-A1 | AZOLO TRIAZINES AND PYRIMIDINES | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-01-29 | — | — | WO | disclosed |