Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ME2 | P23368 | 1/20 | 0.40 |
| ▸ | ME1 | P48163 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316601 | 0.90 | NPY1R (0.53) | NPY1RMAPTMEN1KMT2APOLB | |
| SCHEMBL8314649 | 0.88 | NPY1R (0.54) | NPY1RMAPTMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL8318721 | 0.87 | NPY1R (0.53) | NPY1RMAPTMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL8317459 | 0.87 | MAPT (0.55) | NPY1RMAPTMEN1KMT2APOLB | |
| SCHEMBL8318650 | 0.86 | NPY1R (0.52) | NPY1RMAPTMEN1KMT2APOLB | |
| SCHEMBL8455215 | 0.84 | ALDH1A1 (0.54) | NPY1RMAPTMEN1KMT2APOLB | |
| SCHEMBL7055961 | 0.82 | NPY1R (0.57) | NPY1RMAPTMEN1KMT2APOLB | |
| SCHEMBL7055965 | 0.82 | NPY1R (0.57) | NPY1RMAPTMEN1KMT2APOLB | |
| SCHEMBL7052020 | 0.80 | NPY1R (0.52) | NPY1RMAPTMEN1KMT2APOLB | |
| SCHEMBL7055944 | 0.79 | NPY1R (0.55) | NPY1RMAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985873-A | Certain substituted benzylamine derivatives a new class of Neuropeptide-Y1 specific ligands | NEUROGEN CORPORATION (US) | 1999-11-16 | — | — | US | claimed |
| EP-0915860-A1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE-Y1 SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1999-05-19 | — | — | EP | claimed |
| WO-1998003493-A1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE-Y1 SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1998-01-29 | — | — | WO | claimed |
| US-5985873-A | Certain substituted benzylamine derivatives a new class of Neuropeptide-Y1 specific ligands | NEUROGEN CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |
| EP-0915860-A1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE-Y1 SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003493-A1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE-Y1 SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1998-01-29 | — | — | WO | disclosed |