Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11590449 | 0.95 | ESR1 (0.57) | PPARGKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL4544898 | 0.93 | L3MBTL1 (0.60) | PPARGKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL15851026 | 0.93 | L3MBTL1 (0.60) | PPARGKMT2AHTTSMN1; SMN2TDP1 | |
| Acetaldehyde SCHEMBL27683945 | 0.89 | ESR1 (0.52) | PPARGKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL16756229 | 0.87 | KMT2A (0.64) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL16756223 | 0.83 | ESR1 (0.63) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL8320004 | 0.83 | POLB (0.63) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL10571601 | 0.82 | ESR1 (0.66) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL16756210 | 0.82 | ESR1 (0.66) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL16756220 | 0.82 | ESR1 (0.66) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | disclosed |