Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.63 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4418288 | 1.00 | OXTR (0.63) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL13789768 | 1.00 | OXTR (0.63) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL4418290 | 1.00 | OXTR (0.63) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL4415821 | 0.92 | OXTR (0.61) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL4421839 | 0.92 | OXTR (0.61) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL13789778 | 0.92 | OXTR (0.61) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL8321574 | 0.92 | OXTR (0.61) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL13789770 | 0.92 | OXTR (0.61) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL4415819 | 0.92 | OXTR (0.61) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL4429253 | 0.92 | OXTR (0.61) | OXTRAVPR1AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076407-A2 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2004-09-10 | — | — | WO | disclosed |