Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 2/20 | 0.43 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995342 | 0.88 | CDC7 (0.50) | LMNANPC1POLBCCNCCDK8 | |
| SCHEMBL6990002 | 0.87 | NPC1 (0.53) | RAB9ANPC1CCNCCDK8CDK19 | |
| SCHEMBL6988867 | 0.83 | ALDH1A1 (0.51) | RAB9ANPC1CCNCCDK8CDK19 | |
| SCHEMBL6992723 | 0.82 | CCNC (0.49) | RAB9ANPC1POLBCCNCCDK8 | |
| SCHEMBL6987743 | 0.81 | HPGD (0.53) | TSHRPOLBHTTSMN1; SMN2KMT2A | |
| SCHEMBL6987742 | 0.79 | HPGD (0.38) | RAB9ANPC1CCNCCDK8CDK19 | |
| SCHEMBL6987226 | 0.78 | CDC7 (0.53) | ADORA2AKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL6989907 | 0.78 | CCNC (0.52) | RAB9ALMNANPC1CCNCCDK8 | |
| SCHEMBL6997444 | 0.77 | EPHX1 (0.43) | LMNAPOLBNAMPTKMT2AALDH1A1 | |
| SCHEMBL6990917 | 0.77 | NPC1 (0.41) | RAB9ANPC1POLBCCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931074-A1 | CONDENSED 4,5,6,7-TETRAHYDROBENZO C]THIOPHENES AS ENHANCER FOR CELL DIFFERENTIATION INDUCTION FACTOR ACTION | Takeda Chemical Industries, Ltd. (JP) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998009958-A1 | CONDENSED 4,5,6,7-TETRAHYDROBENZO[C]THIOPHENES AS ENHANCER FOR CELL DIFFERENTIATION INDUCTION FACTOR ACTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-12 | — | — | WO | disclosed |