Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 12/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 17/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7159632 | 0.94 | ITGB3 (0.40) | ITGAVITGB3ITGA2B | |
| SCHEMBL13170305 | 0.87 | HSD17B10 (0.47) | ITGAVMAPTTSHRHSD17B10ITGB3 | |
| SCHEMBL7368163 | 0.86 | BACE1 (0.39) | ITGAVMAPTTSHRHSD17B10ITGB3 | |
| SCHEMBL7163732 | 0.86 | TSHR (0.41) | ITGAVMAPTTSHRHSD17B10ITGB3 | |
| SCHEMBL7163713 | 0.86 | ITGB3 (0.40) | ITGAVMAPTTSHRHSD17B10ITGB3 | |
| SCHEMBL7160779 | 0.85 | ITGB3 (0.45) | ITGAVMAPTTSHRHSD17B10ITGB3 | |
| SCHEMBL7159817 | 0.85 | ITGB3 (0.45) | ITGAVITGB3ITGA2B | |
| SCHEMBL8321280 | 0.84 | ITGB3 (0.37) | ITGAVMAPTTSHRHSD17B10ITGB3 | |
| SCHEMBL7165010 | 0.83 | ITGB3 (0.41) | ITGAVTSHRHSD17B10ITGB3ITGA2B | |
| SCHEMBL4685325 | 0.82 | TSHR (0.38) | ITGAVMAPTTSHRHSD17B10ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803399-B2 | Delivery system for nucleic acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-09-28 | — | — | US | disclosed |
| WO-2004087057-A2 | METHODS FOR INHIBITION OF ANGIOGENESIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2004-10-14 | — | — | WO | disclosed |