Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PPP5C | P53041 | 2/20 | 0.36 |
| ▸ | TFPI2 | P48307 | 2/20 | 0.36 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14709438 | 0.91 | PPP5C (0.38) | ALDH1A1PPP5CTFPI2PPP2CANPY4R | |
| SCHEMBL850229 | 0.78 | POLB (0.43) | ALDH1A1TFPI2TDP1GRM2POLB | |
| SCHEMBL6750346 | 0.78 | CYP2C19 (0.40) | TP53 | |
| SCHEMBL13826247 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNATSHRHSD11B1 | |
| SCHEMBL4686502 | 0.76 | POLB (0.42) | ALDH1A1TFPI2TDP1GRM2POLB | |
| SCHEMBL20031091 | 0.75 | — | — | |
| SCHEMBL13924060 | 0.75 | — | — | |
| SCHEMBL13201847 | 0.75 | — | — | |
| SCHEMBL255097 | 0.75 | — | — | |
| SCHEMBL29950626 | 0.74 | POLB (0.40) | ALDH1A1TFPI2TDP1GRM2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |