Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.40 |
| ▸ | MMP2 | P08253 | 17/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317378 | 0.87 | MMP13 (0.52) | MMP13MMP2MMP1MMP9ADAM17 | |
| Hydrochloric Acid SCHEMBL6232519 | 0.86 | MMP13 (0.51) | MMP13MMP2MMP1MMP9ADAM17 | |
| SCHEMBL6229683 | 0.86 | NPC1 (0.39) | MMP13MMP2MMP1MMP9ADAM17 | |
| SCHEMBL8316792 | 0.85 | MMP13 (0.43) | MMP13MMP2MMP1MMP9ADAM17 | |
| SCHEMBL6263388 | 0.85 | MMP13 (0.41) | MMP13MMP2MMP1MMP9ADAM17 | |
| SCHEMBL6232760 | 0.84 | MMP13 (0.39) | MMP13MMP2MMP1MMP9ADAM17 | |
| SCHEMBL6207085 | 0.76 | MMP13 (0.43) | MMP13MMP2MMP1MMP9ADAM17 | |
| SCHEMBL8291048 | 0.74 | AOC3 (0.34) | MMP13MMP2MMP1MMP9ADAM17 | |
| SCHEMBL5717530 | 0.74 | MMP13 (0.35) | MMP13MMP2MMP1MMP9ADAM17 | |
| SCHEMBL8312493 | 0.72 | MMP13 (0.47) | MMP13MMP2MMP1MMP9ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048368-A2 | HETEROARYLSULFONYLMETHYL HYDROXAMIC ACIDS AND AMIDES AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2004-06-10 | — | — | WO | disclosed |