Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.77 |
| ▸ | GALR3 | O60755 | 3/20 | 0.75 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.75 |
| ▸ | RAB9A | P51151 | 3/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PDE6D | O43924 | 1/20 | 0.53 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833621 | 0.87 | TNF (0.81) | TNFGALR3NR2F2RAB9AHDAC1 | |
| SCHEMBL231295 | 0.87 | TNF (1.00) | TNFGALR3NR2F2RAB9AHDAC1 | |
| Chlormidazole SCHEMBL148113 | 0.86 | GALR3 (1.00) | TNFGALR3NR2F2RAB9AHDAC1 | |
| Chlormidazole SCHEMBL30402878 | 0.86 | GALR3 (1.00) | TNFGALR3NR2F2RAB9AHDAC1 | |
| SCHEMBL8220572 | 0.84 | TNF (0.77) | TNFGALR3NR2F2RAB9AHDAC1 | |
| SCHEMBL9260111 | 0.84 | TNF (0.77) | TNFGALR3NR2F2RAB9AHDAC1 | |
| SCHEMBL12771519 | 0.84 | GALR3 (1.00) | TNFGALR3NR2F2RAB9AHDAC1 | |
| Chlormidazole SCHEMBL364033 | 0.84 | GALR3 (0.97) | TNFGALR3NR2F2RAB9AHDAC1 | |
| SCHEMBL3974900 | 0.84 | TNF (0.77) | TNFGALR3NR2F2RAB9AHDAC1 | |
| SCHEMBL3974904 | 0.84 | TNF (0.77) | TNFGALR3NR2F2RAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063169-A1 | HYDROXAMID ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-07-29 | — | — | WO | disclosed |