Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 1.00 |
| ▸ | GALR3 | O60755 | 3/20 | 0.79 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.79 |
| ▸ | RAB9A | P51151 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | PDE6D | O43924 | 2/20 | 0.68 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.68 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833621 | 0.90 | TNF (0.81) | TNFGALR3NR2F2RAB9AALDH1A1 | |
| Chlormidazole SCHEMBL148113 | 0.88 | GALR3 (1.00) | TNFGALR3NR2F2RAB9AALDH1A1 | |
| Chlormidazole SCHEMBL30402878 | 0.88 | GALR3 (1.00) | TNFGALR3NR2F2RAB9AALDH1A1 | |
| SCHEMBL1560167 | 0.88 | TNF (0.79) | TNFGALR3NR2F2RAB9AALDH1A1 | |
| SCHEMBL8320197 | 0.87 | TNF (0.77) | TNFGALR3NR2F2RAB9AALDH1A1 | |
| SCHEMBL3974900 | 0.87 | TNF (0.77) | TNFGALR3NR2F2RAB9AALDH1A1 | |
| SCHEMBL12771519 | 0.87 | GALR3 (1.00) | TNFGALR3NR2F2RAB9ANPC1 | |
| SCHEMBL8220572 | 0.87 | TNF (0.77) | TNFGALR3NR2F2RAB9AALDH1A1 | |
| SCHEMBL9260111 | 0.87 | TNF (0.77) | TNFGALR3NR2F2RAB9AALDH1A1 | |
| Chlormidazole SCHEMBL364033 | 0.87 | GALR3 (0.97) | TNFGALR3NR2F2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058525-A1 | NOVEL DYE COMPLEXES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | ZINK IMAGING, LLC | 2008-03-06 | — | — | US | claimed |
| WO-2004078874-A2 | NOVEL DYE COMPLEXES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | POLAROID CORPORATION (US) | 2004-09-16 | — | — | WO | claimed |
| US-20040171817-A1 | Novel dye complexes and use thereof in imaging members and methods | ZINK HOLDINGS LLC | 2004-09-02 | — | — | US | claimed |
| US-20240066023-A1 | Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition | SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) | 2024-02-29 | — | — | US | disclosed |
| WO-2024019541-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 일동제약(주) | 2024-01-25 | — | — | WO | disclosed |
| US-11786520-B2 | Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition | SISTEMA UNIV ANA G MENDEZ INC (US) | 2023-10-17 | — | — | US | disclosed |
| CN-111978301-B | Benzimidazole compound with endothelial lipase inhibition effect and application thereof | 盐城师范学院 | 2022-08-02 | — | — | CN | disclosed |
| US-11311531-B2 | Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition | SISTEMA UNIV ANA G MENDEZ INC (US) | 2022-04-26 | — | — | US | disclosed |
| WO-2022057930-A1 | BENZIMIDAZOLE COMPOUND HAVING ENDOTHELIAL LIPASE INHIBITION EFFECT, AND APPLICATION | 盐城师范学院 | 2022-03-24 | — | — | WO | disclosed |
| US-20210290615-A1 | Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition | SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) | 2021-09-23 | — | — | US | disclosed |
| CN-111978301-A | Benzimidazole compound with endothelial lipase inhibition effect and application thereof | 盐城师范学院 | 2020-11-24 | — | — | CN | disclosed |
| EP-1475408-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM | Bridgestone Corporation (JP) | 2004-11-10 | — | — | EP | disclosed |
| EP-1465888-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED BENZOIMIDAZOLE ANALOGUES | NEUROGEN CORPORATION (US) | 2004-10-13 | — | — | EP | disclosed |
| EP-1465635-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 2-(4-BENZYL-PIPERAZIN-1-YLMETHYL)- AND 2-(4-BENZYL-DIAZEPAN-1-YLMETHYL)-1H-BENZOIMIDAZOLE ANALOGUES | NEUROGEN CORPORATION (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2004078874-A2 | NOVEL DYE COMPLEXES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | POLAROID CORPORATION (US) | 2004-09-16 | — | — | WO | disclosed |
| US-20040171817-A1 | Novel dye complexes and use thereof in imaging members and methods | ZINK HOLDINGS LLC | 2004-09-02 | — | — | US | disclosed |
| US-20030216390-A1 | Melanin concentrating hormone receptor ligands: substituted benzoimidazole analogues | NEUROGEN CORPORATION | 2003-11-20 | — | — | US | disclosed |
| WO-2003060475-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 2-(4-BENZYL-PIPERAZIN-1-YLMETHYL)- AND 2-(4-BENZYL-DIAZEPAN-1-YLMETHYL)-1H-BENZOIMIDAZOLE ANALOGUES | NEUROGEN CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003059289-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED BENZOIMIDAZOLE ANALOGUES | NEUROGEN CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |
| US-5670526-A | ANTIINFLAMMATORY AGENT, IMMUNOSUPPRESSANT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11786520-B2 | Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition | AHNAK, RECQL, NBAS | TNF 4853/4885GALR3 1835/4885NR2F2 1676/4885 |
| US-20030216390-A1 | Melanin concentrating hormone receptor ligands: substituted benzoimidazole analogues | MCHR1, MCHR2, MC1R | TNF 4622/4885GALR3 93/4885NR2F2 1478/4885 |
| US-11311531-B2 | Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition | RECQL, AHNAK, NDUFS1 | TNF 4861/4885GALR3 1947/4885NR2F2 1708/4885 |
| US-20210290615-A1 | Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition | AHNAK, RECQL, NBAS | TNF 4853/4885GALR3 1835/4885NR2F2 1676/4885 |
| US-20080058525-A1 | NOVEL DYE COMPLEXES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | DBI, HSPE1, ABCB7 | TNF 4885/4885GALR3 1369/4885NR2F2 850/4885 |
| US-20240066023-A1 | Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition | AHNAK, RECQL, NBAS | TNF 4853/4885GALR3 1835/4885NR2F2 1676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.