Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1928930 | 0.89 | IDO1 (0.49) | TGM2HTTKEAP1NFE2L2LMNA | |
| SCHEMBL7843281 | 0.85 | HTT (0.47) | TGM2HTTKEAP1NFE2L2LMNA | |
| SCHEMBL12068804 | 0.84 | TNKS (0.49) | HTTKEAP1NFE2L2LMNASMN1; SMN2 | |
| SCHEMBL2348002 | 0.84 | HDAC3 (0.43) | LMNASMN1; SMN2 | |
| SCHEMBL1929560 | 0.83 | NPSR1 (0.50) | IDO1 | |
| SCHEMBL1928800 | 0.81 | IDO1 (0.45) | TGM2HTTLMNASMN1; SMN2IDO1 | |
| SCHEMBL27471674 | 0.81 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2 | |
| SCHEMBL1926400 | 0.81 | IDO1 (0.44) | HTTLMNASMN1; SMN2MMP9IDO1 | |
| SCHEMBL1929552 | 0.79 | ROCK2 (0.51) | LMNASMN1; SMN2IDO1 | |
| SCHEMBL1929111 | 0.79 | IDO1 (0.43) | HTTLMNASMN1; SMN2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904274-A4 | FARNESYL TRANSFERASE INHIBITORS | BIOMEASURE INC (US) | 1999-12-29 | — | — | EP | disclosed |
| EP-0904274-A1 | FARNESYL TRANSFERASE INHIBITORS | Biomeasure Incorporated (US) | 1999-03-31 | — | — | EP | disclosed |
| WO-1997030053-A9 | FARNESYL TRANSFERASE INHIBITORS | — | 1997-10-30 | — | — | WO | disclosed |
| WO-1997030053-A1 | FARNESYL TRANSFERASE INHIBITORS | BIOMEASURE INCORPORATED (US) | 1997-08-21 | — | — | WO | disclosed |