Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676836 | 0.84 | BCHE (0.69) | ACHEBCHESIGMAR1FAAHABCC4 | |
| SCHEMBL6867659 | 0.84 | BCHE (0.69) | ACHEBCHESIGMAR1FAAHABCC4 | |
| SCHEMBL678139 | 0.84 | BCHE (0.69) | ACHEBCHESIGMAR1FAAHABCC4 | |
| SCHEMBL676837 | 0.84 | BCHE (0.69) | ACHEBCHESIGMAR1FAAHABCC4 | |
| SCHEMBL14491004 | 0.80 | ACHE (0.73) | ACHEBCHESIGMAR1FAAHABCC4 | |
| SCHEMBL8265237 | 0.79 | ACHE (0.39) | ACHEBCHESIGMAR1FAAHABCC4 | |
| SCHEMBL8281051 | 0.77 | BCHE (0.66) | ACHEBCHESIGMAR1FAAHABCC4 | |
| SCHEMBL14640874 | 0.76 | BCHE (0.56) | ACHEBCHESIGMAR1FAAHABCC4 | |
| SCHEMBL19608841 | 0.75 | ACHE (0.69) | ACHEBCHESIGMAR1FAAHABCC4 | |
| SCHEMBL14640873 | 0.75 | ACHE (0.57) | ACHEBCHESIGMAR1FAAHABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129549-A1 | Stable lamotrigine pharmaceutical compositions and processes for their preparation | RANBAXY LABORATORIES LIMITED (IN) | 2007-06-07 | — | — | US | disclosed |
| WO-2004082685-A1 | PROCESS FOR THE PREPARATION OF DONEPEZIL AND DERIVATIVES THEREOF | RANBAXY LABORATORIES LIMITED (IN) | 2004-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129549-A1 | Stable lamotrigine pharmaceutical compositions and processes for their preparation | KCNJ1, KCNJ8, KCNJ2 | ACHE 126/4885BCHE 277/4885SIGMAR1 2285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.