Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 4/20 | 0.83 |
| ▸ | AXL | P30530 | 7/20 | 0.72 |
| ▸ | IGF1R | P08069 | 6/20 | 0.70 |
| ▸ | SGK1 | O00141 | 1/20 | 0.59 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.58 |
| ▸ | CDC7 | O00311 | 1/20 | 0.57 |
| ▸ | PLK4 | O00444 | 1/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.57 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.57 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.57 |
| ▸ | PAK4 | O96013 | 1/20 | 0.57 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13745445 | 0.91 | CAMKK2 (1.00) | CAMKK2AXLIGF1RSGK1NEK1 | |
| SCHEMBL13745640 | 0.90 | CAMKK2 (0.67) | CAMKK2AXLIGF1RNEK1CDC7 | |
| SCHEMBL13745434 | 0.89 | CAMKK2 (0.69) | CAMKK2AXLIGF1RDYRK3ROCK2 | |
| SCHEMBL1487600 | 0.88 | CAMKK2 (0.79) | CAMKK2AXLIGF1RPLK4AURKA | |
| SCHEMBL13753939 | 0.87 | CAMKK2 (0.69) | CAMKK2AXLIGF1RRIPK1 | |
| SCHEMBL13746980 | 0.87 | CAMKK2 (0.64) | CAMKK2AXLIGF1RNEK1DYRK3 | |
| SCHEMBL13746383 | 0.87 | CAMKK2 (0.64) | CAMKK2AXLIGF1RNEK1DYRK3 | |
| SCHEMBL13746111 | 0.87 | CAMKK2 (0.64) | CAMKK2AXLIGF1RNEK1DYRK3 | |
| SCHEMBL13745636 | 0.87 | CAMKK2 (0.69) | CAMKK2AXLIGF1RNEK1CDC7 | |
| SCHEMBL13745437 | 0.87 | CAMKK2 (0.66) | CAMKK2AXLIGF1RNEK1DYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215771-A1 | JNK INHIBITORS | GRACZYK PIOTR | 2009-08-27 | — | — | US | disclosed |
| US-20090215771-A1 | JNK INHIBITORS | GRACZYK PIOTR | 2009-08-27 | — | — | US | disclosed |
| US-7432375-B2 | JNK inhibitors | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-10-07 | — | — | US | disclosed |
| US-7432375-B2 | JNK inhibitors | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-10-07 | — | — | US | disclosed |
| WO-2004078756-A2 | JNK INHIBITORS | EISAI CO., LTD. (JP) | 2004-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215771-A1 | JNK INHIBITORS | MAPKAPK2, MAPK1, MAPKAPK3 | CAMKK2 94/4885AXL 3999/4885IGF1R 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.