Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.81 |
| ▸ | HTT | P42858 | 3/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4805229 | 0.96 | KMT2A (0.75) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL8585264 | 0.95 | KMT2A (0.72) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL12536537 | 0.92 | KMT2A (0.68) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL3760925 | 0.92 | KMT2A (0.68) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL25870585 | 0.87 | KMT2A (0.61) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL29262919 | 0.86 | KMT2A (0.60) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL26866501 | 0.86 | ELANE (0.61) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL23720977 | 0.86 | SMN1; SMN2 (0.59) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL18879707 | 0.86 | KMT2A (0.59) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL14817250 | 0.86 | KMT2A (0.59) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | disclosed |