SCHEMBL8585264

SCHEMBL8585264

COc1ccc(OC(=O)C2CCCCC2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.72
HTT P42858 3/20 0.72
SMN1; SMN2 Q16637 1/20 0.72
TDP1 Q9NUW8 1/20 0.72
POLB P06746 2/20 0.62
ELANE P08246 2/20 0.62
RAB9A P51151 3/20 0.60
NPC1 O15118 2/20 0.60
CASP3 P42574 1/20 0.60
SENP8 Q96LD8 1/20 0.60
SENP7 Q9BQF6 1/20 0.60
SENP6 Q9GZR1 1/20 0.60
HPGD P15428 3/20 0.56
KDM4E B2RXH2 2/20 0.56
MAPT P10636 2/20 0.55
MEN1 O00255 1/20 0.55
ATM Q13315 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.53
ALDH1A1 P00352 3/20 0.52
GAA P10253 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4805229 0.98 KMT2A (0.75) KMT2AHTTSMN1; SMN2TDP1POLB
SCHEMBL8320550 0.95 KMT2A (0.81) KMT2AHTTSMN1; SMN2TDP1POLB
SCHEMBL26866501 0.91 ELANE (0.61) KMT2AHTTSMN1; SMN2TDP1POLB
SCHEMBL12536537 0.91 KMT2A (0.68) KMT2AHTTSMN1; SMN2TDP1POLB
SCHEMBL3760925 0.91 KMT2A (0.68) KMT2AHTTSMN1; SMN2TDP1POLB
SCHEMBL10574401 0.91 KMT2A (0.88) KMT2AHTTSMN1; SMN2TDP1POLB
SCHEMBL8589037 0.87 KMT2A (0.69) KMT2AHTTSMN1; SMN2TDP1POLB
SCHEMBL25870585 0.86 KMT2A (0.61) KMT2AHTTSMN1; SMN2TDP1POLB
SCHEMBL7100273 0.86 KMT2A (0.72) KMT2AHTTSMN1; SMN2TDP1POLB
SCHEMBL18087028 0.85 KMT2A (0.78) KMT2AHTTSMN1; SMN2TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023181907-A1 COMPOUND, COMPOSITION FOR FORMING ANISOTROPIC DYE FILM, ANISOTROPIC DYE FILM, AND OPTICAL ELEMENT 三菱ケミカル株式会社 2023-09-28 WO disclosed
WO-2023063249-A1 COMPOUND, COMPOSITION FOR ANISOTROPIC DYE FILM COMPRISING SAID COMPOUND, ANISOTROPIC DYE FILM, AND OPTICAL ELEMENT 三菱ケミカル株式会社 2023-04-20 WO disclosed
US-10987348-B2 Modulators of ATP-binding cassette transporters VERTEX PHARMACEUTICALS INCORPORATED (US) 2021-04-27 US disclosed
US-10975061-B2 Modulators of ATP-binding cassette transporters VERTEX PHARMACEUTICALS INCORPORATED (US) 2021-04-13 US disclosed
WO-2020196282-A1 ADHESIVE COMPOSITION 住友化学株式会社 2020-10-01 WO disclosed
WO-2020196080-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL CURED FILM, ELLIPTICALLY POLARIZING PLATE, AND ORGANIC EL DISPLAY DEVICE 住友化学株式会社 2020-10-01 WO disclosed
US-20200299578-A1 POLYMERIZABLE COMPOUND HAVING METHOXYMETHYL ACRYLIC GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2020-09-24 US disclosed
US-20200239775-A1 TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2020-07-30 US disclosed
US-20200115366-A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS VERTEX PHARMACEUTICALS INCORPORATED 2020-04-16 US disclosed
US-10570334-B2 Liquid crystal compound, liquid crystal composition, composite material with encapsulated liquid crystal, and liquid crystal display device using same JNC CORPORATION (JP) 2020-02-25 US disclosed
US-20130178471-A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS Vextex Pharmaceuticals Incorporated (US) 2013-07-11 US disclosed
CN-100351308-C Aqueous compositions with polyvalent metal ions and dispersed polymers ROHM & HAAS (US) 2007-11-28 CN disclosed
CN-1854219-A Floor coating composition and floor coating composition additive ROHM & HAAS (US) 2006-11-01 CN disclosed
CN-1854211-A Compatibilization of esters with latices ROHM & HAAS (US) 2006-11-01 CN disclosed
CN-1721473-A Aqueous compositions with polyvalent metal ions and dispersed polymers ROHM & HAAS (US) 2006-01-18 CN disclosed
CN-1230571-A Process of improving leveling of floor polish composition ROHM & HAAS (US) 1999-10-06 CN disclosed
CN-1230579-A Process of improving appearance of floor polish composition ROHM & HAAS (US) 1999-10-06 CN disclosed
WO-1998031697-A1 ARYL C-GLYCOSIDE COMPOUNDS AND SULFATED ESTERS THEREOF SANKYO COMPANY, LIMITED (JP) 1998-07-23 WO disclosed
CN-1135515-A Liquid crystal alkynyl tolane compound, liquid crystal composition and liquid crystal display part CHISSO CORP (JP) 1996-11-13 CN disclosed
CN-1055188-A The anti-roofing clay that washes away of spraying altogether ROHM & HAAS (US) 1991-10-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10987348-B2 Modulators of ATP-binding cassette transporters CFTR, ABCB1, ABCC2 KMT2A 4313/4885HTT 1077/4885SMN1; SMN2 4738/4885
US-10975061-B2 Modulators of ATP-binding cassette transporters CFTR, ABCB1, ABCC2 KMT2A 4313/4885HTT 1077/4885SMN1; SMN2 4738/4885
US-10570334-B2 Liquid crystal compound, liquid crystal composition, composite material with encapsulated liquid crystal, and liquid crystal display device using same SOD1, SLC39A11, MTX1 KMT2A 3670/4885HTT 4512/4885SMN1; SMN2 1062/4885
US-20200115366-A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS CFTR, ABCB1, ABCC2 KMT2A 4313/4885HTT 1077/4885SMN1; SMN2 4738/4885
US-20130178471-A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS CFTR, ABCB1, ABCC2 KMT2A 4313/4885HTT 1077/4885SMN1; SMN2 4738/4885
US-20200299578-A1 POLYMERIZABLE COMPOUND HAVING METHOXYMETHYL ACRYLIC GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, CCND1, CPNE4 KMT2A 1048/4885HTT 4603/4885SMN1; SMN2 3491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.