Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319604 | 0.92 | LMNA (0.40) | LMNAHTTGAATSHRNR4A2 | |
| SCHEMBL8323663 | 0.92 | NPSR1 (0.38) | LMNAHTTGAATSHRNR4A2 | |
| SCHEMBL8320986 | 0.91 | MAPT (0.46) | LMNAHTTTSHRNPC1RAB9A | |
| SCHEMBL8324480 | 0.88 | NR4A2 (0.41) | LMNAHTTGAATSHRNR4A2 | |
| SCHEMBL8319119 | 0.87 | NR4A2 (0.38) | LMNAHTTGAATSHRNR4A2 | |
| SCHEMBL8326080 | 0.80 | CYP1A2 (0.40) | LMNAHTTGAATSHRNR4A2 | |
| SCHEMBL8323510 | 0.80 | HPGD (0.39) | LMNATSHRNR4A2NPC1RAB9A | |
| SCHEMBL8320947 | 0.80 | LMNA (0.41) | LMNAHTTGAANPC1RAB9A | |
| SCHEMBL16098758 | 0.79 | USP2 (0.44) | LMNAHTTGAATSHRNR4A2 | |
| SCHEMBL8322152 | 0.79 | LMNA (0.44) | LMNAHTTGAATSHRNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866594-A | Indole-2-carboxylate derivatives and fungicidal compositions for agricultural or horticultural use containing the derivatives as active component | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0791582-A1 | INDOLE-2-CARBOXYLIC ESTER DERIVATIVES AND AGRICULTURAL AND HORTICULTURAL BACTERIOCIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-08-27 | — | — | EP | disclosed |