SCHEMBL8320680

SCHEMBL8320680

O=[C]C=CCCCCCCCCCCCCCCC=O

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.50
TRPV1 Q8NER1 2/20 0.50
TSHR P16473 2/20 0.44
HIF1A Q16665 1/20 0.43
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7294606 0.78 TSHR (0.42) TSHRMAPT
SCHEMBL548521 0.78 FAAH (0.54) FAAHTRPV1TSHRMAPT
SCHEMBL9696115 0.78 FAAH (0.54) FAAHTRPV1TSHRMAPT
SCHEMBL910497 0.78 FAAH (0.54) FAAHTRPV1TSHRMAPT
SCHEMBL2163660 0.78 FAAH (0.54) FAAHTRPV1TSHRMAPT
SCHEMBL548514 0.78 FAAH (0.54) FAAHTRPV1TSHRMAPT
SCHEMBL19923331 0.78 HMGCR (0.35)
SCHEMBL7352848 0.78 TSHR (0.42) TSHRMAPT
SCHEMBL158906 0.78 FAAH (0.54) FAAHTRPV1TSHRMAPT
SCHEMBL7356392 0.78 TSHR (0.42) TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5942176-A A POLYLACTAMETHER BLOCK POLYMER OF 6-HYDROXYCAPROIC ACID, A HYDROXY-CONTAINING CARBOXYLIC ACID (7-23 CARBONS) AND A POLY-ETHER MONOMER (2-4 CARBONS); EXTREME TEMPERATURE/PRESSURE LUBRICANTS; TIRE CORDS, SEAT BELTS; AIR BAGS; FUZZ; BREAKING TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 1999-08-24 US disclosed