Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.77 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.77 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.77 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.77 |
| ▸ | RXRA | P19793 | 7/20 | 0.51 |
| ▸ | RXRB | P28702 | 6/20 | 0.51 |
| ▸ | RXRG | P48443 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321346 | 0.90 | PTGER1 (0.77) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL8319623 | 0.88 | PTGER1 (0.73) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL8319420 | 0.87 | PTGER1 (1.00) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL8322261 | 0.86 | PTGER1 (0.70) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL8326500 | 0.85 | PTGER1 (0.69) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL8321768 | 0.84 | PTGER1 (0.95) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL8675451 | 0.84 | PTGER1 (0.56) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| SCHEMBL8324836 | 0.83 | PTGER1 (0.92) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL8459732 | 0.83 | PTGER1 (0.66) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL8325546 | 0.82 | PTGER4 (0.68) | PTGER1PTGER4PTGER3PTGER2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |