Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676059 | 0.90 | PTGER1 (0.57) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| SCHEMBL8675205 | 0.88 | PTGER1 (0.71) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| SCHEMBL8675899 | 0.88 | PTGER1 (0.54) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| SCHEMBL8676630 | 0.85 | MTNR1A (0.55) | PTGER1PTGER4PTGER3PTGER2HTT | |
| SCHEMBL8675521 | 0.85 | PTGER1 (0.67) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| SCHEMBL8676443 | 0.84 | PTGER1 (0.51) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| SCHEMBL8677422 | 0.84 | PTGER1 (0.65) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| SCHEMBL8320717 | 0.84 | PTGER1 (0.77) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| SCHEMBL8677124 | 0.83 | MEN1 (0.56) | PTGER1PTGER4PTGER3PTGER2GAA | |
| SCHEMBL8676586 | 0.81 | PTGER1 (0.52) | PTGER1PTGER4PTGER3PTGER2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |