Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926161 | 0.90 | KCNH2 (0.34) | KCNH2EPHA2FLT4GSK3BRARB | |
| SCHEMBL8320916 | 0.89 | EPHA2 (0.33) | KCNH2EPHA2FLT4GSK3BRARB | |
| SCHEMBL8321535 | 0.86 | EPHA2 (0.49) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL8923193 | 0.85 | EPHA2 (0.47) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL8322523 | 0.81 | KMT2A (0.40) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9041483 | 0.80 | EPHA2 (0.42) | KCNH2EPHA2FLT4GSK3BRARB | |
| SCHEMBL8923852 | 0.80 | KMT2A (0.39) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL8625264 | 0.79 | KMT2A (0.60) | KCNH2EPHA2FLT4GSK3BRARB | |
| SCHEMBL5868715 | 0.79 | KMT2A (0.55) | KCNH2EPHA2FLT4GSK3BRARB | |
| SCHEMBL8623001 | 0.79 | KCNH2 (0.54) | KCNH2EPHA2FLT4GSK3BRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |