Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25863100 | 0.73 | ATR (0.33) | ATRLCK | |
| SCHEMBL31290291 | 0.73 | CTSS (0.42) | ATR | |
| SCHEMBL25863102 | 0.72 | ATR (0.36) | ATRLCK | |
| SCHEMBL31124393 | 0.71 | ATR (0.37) | ATR | |
| SCHEMBL20865565 | 0.70 | ATR (0.40) | ATRLCK | |
| SCHEMBL29140715 | 0.67 | ATR (0.36) | ATRLCK | |
| SCHEMBL21132786 | 0.66 | ATR (0.38) | ATRLCK | |
| SCHEMBL31500450 | 0.65 | ATR (0.43) | ATRLCK | |
| SCHEMBL30673347 | 0.65 | ATR (0.43) | ATRLCK | |
| SCHEMBL6124199 | 0.65 | MEN1 (0.43) | ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966473-A1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | Aventis Pharma S.A. (FR) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998038194-A1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1998-09-03 | — | — | WO | disclosed |