Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.67 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.67 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.67 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324001 | 0.90 | PTGER1 (0.54) | PTGER1PTGER4PTGER3PTGER2MEN1 | |
| SCHEMBL8675698 | 0.86 | MEN1 (0.52) | PTGER1PTGER4PTGER3PTGER2MEN1 | |
| SCHEMBL8409637 | 0.84 | PTGER1 (0.57) | PTGER1PTGER4PTGER3PTGER2MEN1 | |
| SCHEMBL8321346 | 0.84 | PTGER1 (0.77) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL8318002 | 0.82 | PTGER1 (0.73) | PTGER1PTGER4PTGER3PTGER2MAPT | |
| SCHEMBL8323835 | 0.82 | PTGER1 (0.73) | PTGER1PTGER4PTGER3PTGER2MAPT | |
| SCHEMBL8324900 | 0.82 | PTGER1 (0.73) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL9058140 | 0.82 | PTGER1 (0.73) | PTGER1PTGER4PTGER3PTGER2MAPT | |
| SCHEMBL8322711 | 0.82 | PTGER1 (0.77) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL8675702 | 0.82 | MAPT (0.50) | PTGER1PTGER4PTGER3PTGER2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | claimed |
| WO-1996011902-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-04-25 | — | — | WO | claimed |
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |
| EP-0733033-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1996011902-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-04-25 | — | — | WO | disclosed |