Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28377419 | 0.88 | MAPT (0.55) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8676066 | 0.84 | ESR1 (0.52) | KMT2AMTNR1BLMNAPTGER1PTGER4 | |
| SCHEMBL8675086 | 0.83 | TDP1 (0.55) | MAPTKMT2AALDH1A1RAB9AMTNR1B | |
| SCHEMBL8324001 | 0.82 | PTGER1 (0.54) | MAPTMEN1KMT2AALDH1A1CYP19A1 | |
| SCHEMBL8677570 | 0.82 | PTGER1 (0.57) | MTNR1BPTGER1TDP1 | |
| SCHEMBL8677652 | 0.82 | PTGER1 (0.49) | KMT2ABCHEMTNR1BPTGER1PTGER4 | |
| SCHEMBL8322249 | 0.82 | PTGER1 (0.67) | MAPTMEN1KMT2AALDH1A1CYP19A1 | |
| SCHEMBL8676387 | 0.81 | PTGER1 (0.62) | KMT2ARAB9ALMNAPTGER1PTGER4 | |
| SCHEMBL8678301 | 0.81 | MTNR1B (0.50) | KMT2AALDH1A1RAB9AMTNR1BLMNA | |
| SCHEMBL8675698 | 0.81 | MEN1 (0.52) | MAPTMEN1KMT2AALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |