SCHEMBL8322342

SCHEMBL8322342

N#CC(C#N)=C/C=C/N1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ RECQL P46063 1/20 0.33
▸ LMNA P02545 1/20 0.31
▸ BLM P54132 1/20 0.31
▸ MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11333089 1.00 KMT2A (0.33) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL8322347 1.00 KMT2A (0.33) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL24421695 0.98 KMT2A (0.34) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL12758229 0.80 RECQL (0.49) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL12310405 0.77 KMT2A (0.46) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL14396159 0.77 KMT2A (0.31) KMT2AMAOB
SCHEMBL14629850 0.77 KMT2A (0.46) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL13904439 0.74 MEN1 (0.34) KMT2AMEN1RECQL
SCHEMBL11326731 0.74 — —
SCHEMBL16634620 0.72 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220144769-A1 COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-12 — — US disclosed
US-9110243-B2 Laminate film, optically compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-08-18 — — US disclosed
US-9110243-B2 Laminate film, optically compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-08-18 — — US disclosed
US-20120251781-A1 LAMINATE FILM, OPTICALLY COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-10-04 — — US disclosed
US-20120251781-A1 LAMINATE FILM, OPTICALLY COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-10-04 — — US disclosed
US-20120140161-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2012-06-07 — — US disclosed
US-20120140161-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2012-06-07 — — US disclosed
US-20110311738-A1 Process of producing cellulose acylate film, cellulose acylate film, polarizing plate liquid crystal display device and optical compensation film FUJIFILM CORPORATION (JP) 2011-12-22 — — US disclosed
US-20110311738-A1 Process of producing cellulose acylate film, cellulose acylate film, polarizing plate liquid crystal display device and optical compensation film FUJIFILM CORPORATION (JP) 2011-12-22 — — US disclosed
EP-0638079-B1 DEAZAAMINOPTERINS FOR TREATMENT OF INFLAMMATION STANFORD RES INST INT (US) 1999-12-15 — — EP disclosed
WO-1993022312-A1 DEAZAAMINOPTERINS FOR TREATMENT OF INFLAMMATION SRI INTERNATIONAL (US) 1993-11-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220144769-A1 COMPOUND CBR3, SFXN3, CBR1 KMT2A 2887/4885MEN1 1793/4885ALDH1A1 928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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