Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310405 | 1.00 | KMT2A (0.46) | KMT2AMAOBSLC16A3SLC16A1ALDH1A1 | |
| SCHEMBL23140678 | 0.85 | RECQL (0.50) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL20805917 | 0.85 | RECQL (0.50) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL23140679 | 0.85 | RECQL (0.50) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL12310408 | 0.80 | RECQL (0.49) | KMT2AMAOBSLC16A3SLC16A1ALDH1A1 | |
| SCHEMBL4544807 | 0.78 | RECQL (0.50) | KMT2ASLC16A1ALDH1A1LMNAMAPT | |
| SCHEMBL8322342 | 0.77 | KMT2A (0.33) | KMT2AMAOBALDH1A1LMNAMAPT | |
| SCHEMBL11333089 | 0.77 | KMT2A (0.33) | KMT2AMAOBALDH1A1LMNAMAPT | |
| SCHEMBL8322347 | 0.77 | KMT2A (0.33) | KMT2AMAOBALDH1A1LMNAMAPT | |
| SCHEMBL15761690 | 0.76 | MCL1 (0.38) | KMT2AMAOBALDH1A1MCL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2734180-B1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES | OREAL (FR) | 2021-03-31 | — | — | EP | claimed |
| EP-2734180-B1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES | OREAL (FR) | 2021-03-31 | — | — | EP | disclosed |
| EP-2734499-B1 | MEROCYANINE DERIVATIVES | BASF SE (DE) | 2020-06-24 | — | — | EP | disclosed |
| US-20150284330-A1 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | OREAL (FR) | 2015-10-08 | — | — | US | disclosed |
| US-8961941-B2 | Composition comprising a dibenzoylmethane screening agent and a merocyanine dicyano or cyanoacetate derivative; method for the photostabilization of the dibenzoylmethane screening agent | L'OREAL (FR) | 2015-02-24 | — | — | US | disclosed |
| US-20130064871-A1 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | L'OREAL (FR) | 2013-03-14 | — | — | US | disclosed |
| EP-2547314-A2 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | L'Oréal (FR) | 2013-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130064871-A1 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | DDT, PCCA, DDC | KMT2A 1784/4885MAOB 1806/4885SLC16A3 259/4885 |
| US-20150284330-A1 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | DDT, PCCA, DDC | KMT2A 1784/4885MAOB 1806/4885SLC16A3 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.