Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320026 | 1.00 | ELANE (0.40) | ELANEBCHEACHEALDH1A1MAPT | |
| SCHEMBL8325529 | 0.94 | ELANE (0.36) | ELANEBCHEACHEALDH1A1MAPT | |
| SCHEMBL8321674 | 0.94 | ELANE (0.36) | ELANEBCHEACHEALDH1A1MAPT | |
| SCHEMBL8322215 | 0.88 | ELANE (0.50) | ELANEACHEMEN1KMT2ACYP3A4 | |
| SCHEMBL8649502 | 0.87 | GRM2 (0.33) | ELANEBCHEACHECYP3A4CA2 | |
| SCHEMBL13131239 | 0.87 | ELANE (0.46) | ELANEBCHEACHEALDH1A1MAPT | |
| SCHEMBL8322200 | 0.87 | ELANE (0.46) | ELANEBCHEACHEALDH1A1MAPT | |
| SCHEMBL8322957 | 0.87 | ELANE (0.54) | ELANEALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8323431 | 0.87 | ELANE (0.54) | ELANEALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8319103 | 0.82 | MAPT (0.40) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |