Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13131239 | 1.00 | ELANE (0.46) | ELANECYP3A4CA2LMNAKDM1A | |
| SCHEMBL8322215 | 0.95 | ELANE (0.50) | ELANECYP3A4CA2LMNAKDM1A | |
| SCHEMBL8324994 | 0.93 | ELANE (0.41) | ELANECYP3A4CA2LMNAKDM1A | |
| SCHEMBL8325779 | 0.89 | ELANE (0.44) | ELANECYP3A4CA2LMNAKDM1A | |
| SCHEMBL8322360 | 0.87 | ELANE (0.40) | ELANECYP3A4CA2LMNAKDM1A | |
| SCHEMBL8320026 | 0.87 | ELANE (0.40) | ELANECYP3A4CA2LMNAKDM1A | |
| SCHEMBL8322043 | 0.86 | ELANE (0.58) | ELANECA2KDM1AMEN1KMT2A | |
| SCHEMBL795385 | 0.86 | ELANE (0.58) | ELANECA2KDM1AMEN1KMT2A | |
| SCHEMBL8643877 | 0.86 | ELANE (0.36) | ELANECYP3A4CA2ACHEBCHE | |
| SCHEMBL8648378 | 0.85 | CYP3A4 (0.36) | ELANECYP3A4CA2LMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |