Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.90 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.74 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.74 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8609483 | 1.00 | ADORA2A (0.90) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8326918 | 1.00 | ADORA2A (0.90) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8330283 | 0.96 | ADORA2A (0.85) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8324807 | 0.96 | ADORA2A (0.85) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8608676 | 0.96 | ADORA2A (0.85) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8607047 | 0.96 | ADORA2A (0.85) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8328289 | 0.96 | ADORA2A (0.85) | ADORA2AADORA3ADORA2BADORA1 | |
| Hydrochloric Acid SCHEMBL8609323 | 0.95 | ADORA2A (0.84) | ADORA2AADORA3ADORA2BADORA1 | |
| Hydrochloric Acid SCHEMBL8324271 | 0.95 | ADORA2A (0.84) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8609426 | 0.95 | ADORA2A (1.00) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925624-A | ANTIINFLAMMATORY AGENTS TREATING PATIENTS WITH INFLAMMATORY CONDITIONS SUSCEPTIBLE TO LEUKOCYTE-INDUCED TISSUE DAMAGE | GLAXO GROUP LIMITED (GB) | 1999-07-20 | — | — | US | disclosed |
| US-5889178-A | N-(2,2-DIPHENYLETHYL)-DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-03-30 | — | — | US | disclosed |
| EP-0680488-B1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LTD (GB) | 1998-04-08 | — | — | EP | disclosed |
| EP-0680488-A1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017090-A1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1994-08-04 | — | — | WO | disclosed |