Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.85 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.72 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324807 | 1.00 | ADORA2A (0.85) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8607047 | 1.00 | ADORA2A (0.85) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8330283 | 1.00 | ADORA2A (0.85) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8328289 | 1.00 | ADORA2A (0.85) | ADORA2AADORA3ADORA2BADORA1 | |
| Hydrochloric Acid SCHEMBL8609323 | 0.99 | ADORA2A (0.84) | ADORA2AADORA3ADORA2BADORA1 | |
| Hydrochloric Acid SCHEMBL8324271 | 0.99 | ADORA2A (0.84) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8609483 | 0.96 | ADORA2A (0.90) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8326918 | 0.96 | ADORA2A (0.90) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8322788 | 0.96 | ADORA2A (0.90) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8322018 | 0.93 | ADORA2A (0.88) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680488-B1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LTD (GB) | 1998-04-08 | — | — | EP | disclosed |