SCHEMBL8322797

SCHEMBL8322797

CCCCCCNCC#Cc1cccc(-c2c(NC(=O)Nc3c(C(C)C)cccc3C(C)C)c(=O)n(CCCC)c3ncccc23)c1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACAT1 P24752 1/20 0.60
SOAT1 P35610 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8325244 0.94 ACAT1 (0.62) ACAT1SOAT1
SCHEMBL8322807 0.93 ACAT1 (0.57) ACAT1SOAT1
SCHEMBL8326104 0.92 ACAT1 (0.62) ACAT1SOAT1
SCHEMBL8326315 0.91 ACAT1 (0.65) ACAT1SOAT1
SCHEMBL8326398 0.91 ACAT1 (0.62) ACAT1SOAT1
SCHEMBL8325569 0.91 ACAT1 (0.64) ACAT1SOAT1
SCHEMBL8328138 0.90 ACAT1 (0.58) ACAT1SOAT1
SCHEMBL8326879 0.90 ACAT1 (0.58) ACAT1SOAT1
SCHEMBL8326943 0.90 ACAT1 (0.58) ACAT1SOAT1
SCHEMBL8324340 0.89 ACAT1 (0.61) ACAT1SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0947515-A1 NOVEL NAPHTHYRIDINE DERIVATIVES SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1999-10-06 EP disclosed