Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325094 | 0.93 | DPP4 (0.64) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL8322847 | 0.90 | DPP4 (0.62) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL9572096 | 0.90 | DPP4 (0.62) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL11022634 | 0.87 | DPP4 (0.68) | DPP4CHRM2DRD1DHFRLMNA | |
| Hydrochloric Acid SCHEMBL20394712 | 0.86 | DPP4 (0.67) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL10377708 | 0.86 | DPP4 (0.66) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL8775460 | 0.86 | DPP4 (0.64) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL2114896 | 0.85 | DPP4 (0.59) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL8323268 | 0.85 | DPP4 (0.59) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL8322856 | 0.85 | DPP4 (0.59) | DPP4CHRM2DRD1DHFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641339-B1 | AZASPIRO QUINOLONE ANTIBACTERIAL AGENTS | PFIZER (US) | 1999-09-15 | — | — | EP | disclosed |
| US-5407943-A | Azaspiro quinolone antibacterial agents | PFIZER INC. (US) | 1995-04-18 | — | — | US | disclosed |