Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | DHFR | P00374 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | EDNRA | P25101 | 1/20 | 0.55 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 4/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10377719 | 0.99 | DPP4 (0.65) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL10377337 | 0.99 | DPP4 (0.65) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL11020192 | 0.91 | LMNA (0.64) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL11020756 | 0.91 | DPP4 (0.59) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL10377364 | 0.90 | DPP4 (0.62) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL11022634 | 0.90 | DPP4 (0.68) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL10377610 | 0.90 | DPP4 (0.62) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL10377621 | 0.90 | DPP4 (0.62) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL311935 | 0.90 | LMNA (0.68) | DPP4CHRM2DRD1DHFRLMNA | |
| Hydrochloric Acid SCHEMBL10551866 | 0.89 | DPP4 (0.61) | DPP4CHRM2DRD1DHFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153828-B1 | 1-CYCLOPROPYL-1, 4-DIHYDRO-6-FLUORO-4-OXO-1, 8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS; THEIR DERIVATIVES AND A PROCESS FOR PREPARING THE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1990-12-27 | — | — | EP | claimed |
| CN-1003236-B | Preparation method of 6, 7-disubstituted-1-cyclopropyl-1, 4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic acid | 拜尔公司 | 1989-02-08 | — | — | CN | claimed |
| EP-1620098-B1 | USE OF OXAZOLIDINONE-QUINOLINE HYBRID ANTIBIOTICS FOR THE TREATMENT OF ANTHRAX AND OTHER INFECTIONS | MORPHOCHEM AG KOMB CHEMIE (DE) | 2008-06-11 | — | — | EP | disclosed |
| US-20070004769-A1 | Intermediate products for producing oxazolidinone-quinolone hybrids | MORPHOCHEM AKTIEGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2007-01-04 | — | — | US | disclosed |
| EP-0153828-B1 | 1-CYCLOPROPYL-1, 4-DIHYDRO-6-FLUORO-4-OXO-1, 8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS; THEIR DERIVATIVES AND A PROCESS FOR PREPARING THE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4840954-A | BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| US-4663457-A | BACTERICIDES | WARNER-LAMBERT COMPANY (US) | 1987-05-05 | — | — | US | disclosed |
| CN-86100126-A | 6, the two replacement-1-cyclopropyl of 7--1,4 dihydro-4-oxo-1, the preparation method and the application thereof of 8-naphthyridines-3-carboxylic acid | — | 1986-07-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004769-A1 | Intermediate products for producing oxazolidinone-quinolone hybrids | OXA1L, NQO1, NQO2 | DPP4 1507/4885CHRM2 4404/4885DRD1 1041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.