Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19662088 | 0.84 | KCNH2 (0.50) | PTGES2HRH3KCNH2PRKAB2PRKAG1 | |
| SCHEMBL27714170 | 0.83 | NCF1 (0.40) | PTGES2HRH3KCNH2LOXL2ADORA2A | |
| SCHEMBL23662544 | 0.81 | KCNH2 (0.44) | PTGES2HRH3KCNH2LTA4HPRKAB2 | |
| SCHEMBL23647789 | 0.81 | KCNH2 (0.44) | PTGES2HRH3KCNH2LTA4HPRKAB2 | |
| SCHEMBL13179084 | 0.81 | KCNH2 (0.44) | PTGES2HRH3KCNH2PRKAB2PRKAG1 | |
| SCHEMBL13179110 | 0.81 | KCNH2 (0.44) | PTGES2HRH3KCNH2PRKAB2PRKAG1 | |
| SCHEMBL27011187 | 0.79 | KCNH2 (0.44) | PTGES2HRH3KCNH2PRKAB2PRKAG1 | |
| SCHEMBL30912579 | 0.79 | KCNH2 (0.44) | PTGES2HRH3KCNH2PRKAB2PRKAG1 | |
| SCHEMBL20168374 | 0.77 | HRH3 (0.39) | HRH3LTA4HLOXL2CSNK2A1ABAT | |
| SCHEMBL22689629 | 0.76 | KCNH2 (0.46) | PTGES2HRH3KCNH2LTA4HPRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067522-A1 | AZAPHENYLALANINE DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | LEK PHARMACEUTICALS D.D. (SI) | 2004-08-12 | — | — | WO | disclosed |