Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1999145 | 0.81 | BUB1 (0.32) | HTTATML3MBTL1 | |
| SCHEMBL234224 | 0.72 | KDM4E (0.30) | — | |
| SCHEMBL8325790 | 0.65 | MEN1 (0.38) | HTTATML3MBTL1 | |
| SCHEMBL7214509 | 0.65 | IDO1 (0.41) | — | |
| SCHEMBL6015851 | 0.64 | HTT (0.38) | HTTATML3MBTL1 | |
| SCHEMBL8319230 | 0.64 | HTT (0.38) | HTTATML3MBTL1 | |
| SCHEMBL8323502 | 0.63 | HTR2A (0.36) | — | |
| SCHEMBL8323489 | 0.63 | HTR2A (0.36) | — | |
| SCHEMBL8323495 | 0.63 | HTR2A (0.36) | — | |
| SCHEMBL9382372 | 0.62 | DRD3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470490-B1 | Substituted pyrroles | HOFFMANN LA ROCHE (CH) | 1999-05-06 | — | — | EP | disclosed |
| US-5292747-A | Substituted pyrroles | HOFFMAN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0470490-A1 | Substituted pyrroles | F. HOFFMANN-LA ROCHE AG (CH) | 1992-02-12 | — | — | EP | disclosed |