SCHEMBL8323523

SCHEMBL8323523

CCc1nc2c(C)cc(C)nc2n1Cc1ccc2nc(C3=CC=CCC3=C=O)cc(C(=O)O)c2c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8327383 0.80
SCHEMBL8323529 0.79
SCHEMBL8323527 0.77
SCHEMBL8325457 0.72
SCHEMBL7376048 0.72
SCHEMBL6558915 0.71
SCHEMBL4328034 0.70
SCHEMBL5420235 0.70
SCHEMBL683347 0.70 AGTR1 (0.67)
SCHEMBL9136610 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0709377-B1 Process for producing quinolin-2-yl benzoic acid compounds ASAHI GLASS CO LTD (JP) 1999-09-29 EP disclosed
US-5780634-A Process for producing 2-(carboxyphenyl)-4-quinolinecarboxylic acid compounds THE GREEN CROSS CORPORATION (JP) 1998-07-14 US disclosed
EP-0709377-A1 Process for producing quinolin-2-yl benzoic acid compounds ASAHI GLASS COMPANY LTD. (JP) 1996-05-01 EP disclosed