Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 8/20 | 0.66 |
| ▸ | GNAI3 | P08754 | 7/20 | 0.66 |
| ▸ | GNAI1 | P63096 | 7/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | EBP | Q15125 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324109 | 1.00 | GNAO1 (0.66) | GNAO1GNAI3GNAI1SIGMAR1EBP | |
| SCHEMBL8321113 | 1.00 | GNAO1 (0.66) | GNAO1GNAI3GNAI1SIGMAR1EBP | |
| SCHEMBL8325801 | 1.00 | GNAO1 (0.66) | GNAO1GNAI3GNAI1SIGMAR1EBP | |
| SCHEMBL8318619 | 1.00 | GNAO1 (0.66) | GNAO1GNAI3GNAI1SIGMAR1EBP | |
| SCHEMBL26157407 | 1.00 | GNAO1 (0.66) | GNAO1GNAI3GNAI1SIGMAR1EBP | |
| SCHEMBL2953638 | 1.00 | GNAO1 (0.66) | GNAO1GNAI3GNAI1SIGMAR1EBP | |
| SCHEMBL8322301 | 1.00 | GNAO1 (0.66) | GNAO1GNAI3GNAI1SIGMAR1EBP | |
| SCHEMBL10442393 | 1.00 | GNAO1 (0.66) | GNAO1GNAI3GNAI1SIGMAR1EBP | |
| Hydrochloric Acid SCHEMBL30330982 | 0.98 | GNAO1 (0.69) | GNAO1GNAI3GNAI1SIGMAR1EBP | |
| Fluoride SCHEMBL30330675 | 0.98 | GNAO1 (0.63) | GNAO1GNAI3GNAI1SIGMAR1EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |
| EP-0604494-B1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1999-07-28 | — | — | EP | disclosed |