Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30227192 | 0.79 | SLC7A5 (0.33) | — | |
| SCHEMBL4787909 | 0.77 | GRM2 (0.31) | GRM2GRM3 | |
| SCHEMBL27782639 | 0.74 | MAPT (0.31) | — | |
| SCHEMBL7994714 | 0.72 | GRM2 (0.38) | GRM2GRM3 | |
| SCHEMBL16222522 | 0.71 | — | — | |
| SCHEMBL16222700 | 0.71 | — | — | |
| SCHEMBL5265880 | 0.71 | RNPEP (0.32) | — | |
| SCHEMBL8337054 | 0.71 | — | — | |
| SCHEMBL11213746 | 0.70 | — | — | |
| SCHEMBL5688803 | 0.70 | GRM2 (0.34) | GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633259-B1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | HOFFMANN LA ROCHE (CH) | 1999-01-13 | — | — | EP | disclosed |
| EP-0816309-A1 | Scavenger assisted combinatorial process for preparing libraries of urea and thiourea compounds | ELI LILLY AND COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0633259-A1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | F. HOFFMANN-LA ROCHE AG (CH) | 1995-01-11 | — | — | EP | disclosed |