SCHEMBL7994714

SCHEMBL7994714

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nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.38
GRM3 Q14832 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27495726 0.80 MMP8 (0.33)
SCHEMBL7167300 0.80 MMP8 (0.33)
SCHEMBL8323608 0.72 GRM2 (0.33) GRM2GRM3
SCHEMBL15327594 0.70
SCHEMBL7186091 0.69 CYP1A2 (0.34)
Hydrochloric Acid SCHEMBL7210374 0.69
SCHEMBL5696055 0.69 GRM2 (0.43) GRM2GRM3
SCHEMBL29193259 0.68
SCHEMBL29193261 0.68
SCHEMBL21821202 0.68 GRM2 (0.46) GRM2GRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284777-B1 BONE DISORDERS SMITHKLINE BEECHAM CORPORATION 2001-09-04 US disclosed