Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 6/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326222 | 0.93 | KCNH2 (0.43) | KCNH2POLBALDH1A1OPRM1CHRM2 | |
| SCHEMBL8322363 | 0.90 | KCNH2 (0.38) | KCNH2POLBALDH1A1OPRM1CHRM2 | |
| SCHEMBL8323667 | 0.90 | ALDH1A1 (0.49) | KCNH2POLBALDH1A1OPRM1CHRM2 | |
| SCHEMBL8322362 | 0.86 | KCNH2 (0.51) | KCNH2POLBALDH1A1OPRM1KDM4E | |
| SCHEMBL8323321 | 0.86 | KCNH2 (0.35) | KCNH2POLBALDH1A1OPRM1CHRM2 | |
| SCHEMBL8323314 | 0.81 | PIK3CG (0.44) | ALDH1A1TOP2ATOP2BKDM4EHPGD | |
| SCHEMBL8324813 | 0.80 | KCNH2 (0.53) | KCNH2POLBALDH1A1OPRM1CHRM2 | |
| SCHEMBL8923177 | 0.78 | KCNH2 (0.51) | KCNH2POLBALDH1A1OPRM1CHRM2 | |
| SCHEMBL8923183 | 0.77 | KCNH2 (0.43) | KCNH2POLBALDH1A1OPRM1CHRM2 | |
| SCHEMBL8327861 | 0.77 | ALDH1A1 (0.63) | KCNH2POLBALDH1A1OPRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |