Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 18/20 | 0.83 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.67 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.61 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | GALR3 | O60755 | 1/20 | 0.58 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033304 | 0.91 | ADK (1.00) | ADKHASPINSLC29A1 | |
| Iodotubercidin SCHEMBL2786488 | 0.91 | ADK (0.83) | ADKHASPINSLC29A1DOT1LNPC1 | |
| Iodotubercidin SCHEMBL12505209 | 0.91 | ADK (0.83) | ADKHASPINSLC29A1DOT1LNPC1 | |
| Iodotubercidin SCHEMBL12652819 | 0.91 | ADK (0.83) | ADKHASPINSLC29A1DOT1LNPC1 | |
| Iodotubercidin SCHEMBL319225 | 0.91 | ADK (0.83) | ADKHASPINSLC29A1DOT1LNPC1 | |
| Iodotubercidin SCHEMBL13021361 | 0.91 | ADK (0.83) | ADKHASPINSLC29A1DOT1LNPC1 | |
| Iodotubercidin SCHEMBL16978206 | 0.91 | ADK (0.83) | ADKHASPINSLC29A1DOT1LNPC1 | |
| SCHEMBL8333514 | 0.91 | ADK (1.00) | ADKHASPINSLC29A1 | |
| Iodotubercidin SCHEMBL8328935 | 0.91 | ADK (0.83) | ADKHASPINSLC29A1DOT1LNPC1 | |
| Iodotubercidin SCHEMBL29375718 | 0.91 | ADK (0.83) | ADKHASPINSLC29A1DOT1LNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496617-B1 | Adenosine kinase inhibitors | METABASIS THERAPEUTICS INC (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5646128-A | TREATING INFLAMMATION, SEPSIS, SEPTIC SHOCK, BURNS | GENSIA, INC. (US) | 1997-07-08 | — | — | US | disclosed |
| WO-1994017803-A9 | ADENOSINE KINASE INHIBITORS | — | 1994-09-29 | — | — | WO | disclosed |
| WO-1992012718-A1 | ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1992-08-06 | — | — | WO | disclosed |
| EP-0496617-A1 | Adenosine kinase inhibitors | GENSIA, INC. (US) | 1992-07-29 | — | — | EP | disclosed |