Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312354 | 0.89 | HSD17B10 (0.37) | MEN1KMT2AGRM4 | |
| SCHEMBL7312361 | 0.89 | HSD17B10 (0.37) | MEN1KMT2AGRM4 | |
| SCHEMBL7311245 | 0.89 | HSD17B10 (0.37) | MEN1KMT2AGRM4 | |
| SCHEMBL9487213 | 0.89 | HSD17B10 (0.37) | MEN1KMT2AGRM4 | |
| SCHEMBL7395961 | 0.89 | HSD17B10 (0.37) | MEN1KMT2AGRM4 | |
| Hydrochloric Acid SCHEMBL8323728 | 0.87 | HSD17B10 (0.36) | MEN1KMT2AGRM4 | |
| SCHEMBL7311217 | 0.84 | KDM4E (0.39) | MEN1KMT2A | |
| SCHEMBL7318335 | 0.84 | KDM4E (0.39) | MEN1KMT2A | |
| SCHEMBL7317482 | 0.84 | KDM4E (0.39) | MEN1KMT2A | |
| SCHEMBL7317477 | 0.84 | KDM4E (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955470-A | Derivatives of amide analogs of certain methano bridged quinolizines | MERRELL PHARMACEUTICALS, INC. (US) | 1999-09-21 | — | — | US | disclosed |
| EP-0518767-A2 | Derivatives of amide analogs of certain methano bridged quinolizines | MERRELL PHARMACEUTICALS INC. (US) | 1992-12-16 | — | — | EP | disclosed |