Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380145 | 0.96 | FKBP1A (0.47) | TSHRFABP7FABP5SMN1; SMN2CYP2C19 | |
| SCHEMBL30852824 | 0.93 | TSHR (0.45) | TSHRFABP7FABP5SMN1; SMN2CYP2C19 | |
| SCHEMBL2392378 | 0.85 | TSHR (0.46) | TSHRFABP7FABP5SMN1; SMN2CYP2C19 | |
| SCHEMBL29845766 | 0.84 | FKBP1A (0.47) | TSHRFABP7FABP5SMN1; SMN2CYP2C19 | |
| Hydrochloric Acid SCHEMBL6543330 | 0.83 | TSHR (0.48) | TSHRFABP7FABP5SMN1; SMN2CYP2C19 | |
| SCHEMBL29845815 | 0.83 | FKBP1A (0.46) | TSHRFABP7FABP5SMN1; SMN2CYP2C19 | |
| SCHEMBL27868267 | 0.81 | TSHR (0.43) | TSHRFABP7FABP5SMN1; SMN2CYP2C19 | |
| SCHEMBL28126888 | 0.80 | FKBP1A (0.43) | TSHRFABP7FABP5SMN1; SMN2CYP2C19 | |
| SCHEMBL27660459 | 0.80 | FABP7 (0.47) | TSHRFABP7FABP5SMN1; SMN2CYP2C19 | |
| SCHEMBL6380142 | 0.79 | FKBP1A (0.43) | TSHRFABP7FABP5SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925624-A | ANTIINFLAMMATORY AGENTS TREATING PATIENTS WITH INFLAMMATORY CONDITIONS SUSCEPTIBLE TO LEUKOCYTE-INDUCED TISSUE DAMAGE | GLAXO GROUP LIMITED (GB) | 1999-07-20 | — | — | US | disclosed |
| US-5889178-A | N-(2,2-DIPHENYLETHYL)-DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-03-30 | — | — | US | disclosed |