Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27491543 | 0.86 | TDP1 (0.53) | TDP1FFAR4FFAR1POLBAPEX1 | |
| SCHEMBL7795998 | 0.83 | TDP1 (0.58) | TDP1FFAR4FFAR1POLBAPEX1 | |
| SCHEMBL8330974 | 0.81 | FFAR4 (0.48) | FFAR4FFAR1HRH3RORC | |
| SCHEMBL16742113 | 0.78 | TDP1 (0.66) | TDP1POLBAPEX1RECQLHRH3 | |
| SCHEMBL8936900 | 0.77 | TDP1 (0.57) | TDP1POLBAPEX1RECQL | |
| SCHEMBL9188629 | 0.77 | TDP1 (0.57) | TDP1POLBAPEX1RECQL | |
| SCHEMBL8042033 | 0.75 | FFAR4 (0.43) | FFAR4FFAR1 | |
| SCHEMBL8042036 | 0.75 | AR (0.46) | — | |
| SCHEMBL7627993 | 0.73 | TDP1 (0.52) | TDP1ALDH1A1 | |
| SCHEMBL8131638 | 0.71 | TDP1 (0.56) | TDP1POLBAPEX1RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |