Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 8/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795630 | 0.88 | FFAR4 (0.60) | FFAR4FFAR1RORC | |
| SCHEMBL8323907 | 0.81 | TDP1 (0.53) | FFAR4FFAR1RORCHRH3 | |
| SCHEMBL13802286 | 0.73 | FFAR1 (0.56) | FFAR4FFAR1RORCHRH3 | |
| SCHEMBL7795628 | 0.72 | CXCR2 (0.39) | FFAR4FFAR1DRD2HTR1DDRD3 | |
| SCHEMBL3905377 | 0.72 | HRH3 (0.51) | FFAR4FFAR1HRH3 | |
| SCHEMBL8042033 | 0.71 | FFAR4 (0.43) | FFAR4FFAR1 | |
| SCHEMBL4100172 | 0.71 | DRD2 (0.48) | DRD2HTR1DDRD3HSD11B1 | |
| SCHEMBL17834378 | 0.70 | PPARA (0.41) | FFAR1 | |
| SCHEMBL1602268 | 0.69 | DRD2 (0.51) | DRD2DRD3 | |
| SCHEMBL8042036 | 0.69 | AR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |