Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 8/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4163700 | 0.94 | SLC22A12 (0.34) | DDR1SLC22A12CNR1ALDH1A1SLC22A6 | |
| SCHEMBL3000283 | 0.91 | SLC22A12 (0.36) | DDR1SLC22A12CNR1ALDH1A1SLC22A6 | |
| SCHEMBL3000286 | 0.91 | SLC22A12 (0.36) | DDR1SLC22A12CNR1ALDH1A1SLC22A6 | |
| SCHEMBL2991101 | 0.83 | ALDH1A1 (0.38) | DDR1SLC22A12ALDH1A1MEN1ALOX12 | |
| SCHEMBL2991103 | 0.83 | ALDH1A1 (0.38) | DDR1SLC22A12ALDH1A1MEN1ALOX12 | |
| SCHEMBL4153302 | 0.83 | SLC22A12 (0.34) | DDR1SLC22A12CNR1ALDH1A1LMNA | |
| SCHEMBL14177358 | 0.83 | ALDH1A1 (0.41) | DDR1SLC22A12ALDH1A1MEN1ALOX12 | |
| SCHEMBL14277099 | 0.83 | ALDH1A1 (0.41) | DDR1SLC22A12ALDH1A1MEN1ALOX12 | |
| SCHEMBL3001627 | 0.83 | SLC22A12 (0.33) | SLC22A12ALDH1A1MEN1ALOX12APOBEC3A | |
| SCHEMBL6253016 | 0.83 | SLC22A12 (0.33) | SLC22A12ALDH1A1MEN1ALOX12APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058743-A1 | NOVEL SUBSTITUTED NITROGEN-CONTAINING HETEROBICYCLES AND USE THEREOF AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-15 | — | — | WO | disclosed |