Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323681 | 0.93 | MAPT (0.49) | MAPTTP53MEN1KMT2APDE4B | |
| Hydrochloric Acid SCHEMBL8330804 | 0.92 | MAPT (0.49) | MAPTTP53PKMMEN1KMT2A | |
| SCHEMBL8328843 | 0.91 | MEN1 (0.42) | MAPTDHODHMEN1PABPC1KMT2A | |
| SCHEMBL8329674 | 0.90 | MAPT (0.43) | MAPTDHODHKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8561030 | 0.84 | MAPT (0.56) | MAPTTP53PDE4BTHRBKDM4E | |
| SCHEMBL8564146 | 0.83 | CSF1R (0.50) | MAPTMEN1KMT2APDE4BTHRB | |
| Hydrochloric Acid SCHEMBL8625846 | 0.83 | MAPT (0.55) | MAPTTP53PDE4BTHRBKDM4E | |
| SCHEMBL8327883 | 0.82 | MAPT (0.48) | MAPTTP53MEN1KMT2APDE4B | |
| SCHEMBL8328461 | 0.82 | MAPT (0.52) | MAPTTP53PDE4BTHRBALDH1A1 | |
| Hydrochloric Acid SCHEMBL8327246 | 0.81 | MAPT (0.47) | MAPTTP53MEN1KMT2APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |