Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328461 | 0.92 | MAPT (0.52) | MAPTPTGS2SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL8328640 | 0.92 | MAPT (0.51) | MAPTPTGS2SMN1; SMN2NPC1KDM4E | |
| SCHEMBL8323951 | 0.90 | MAPT (0.41) | MAPTDHODHP2RX3SMN1; SMN2KDM4E | |
| SCHEMBL8564146 | 0.85 | CSF1R (0.50) | MAPTSMN1; SMN2NPC1KMT2ANPSR1 | |
| SCHEMBL8328465 | 0.85 | PTGS2 (0.40) | MAPTDHODHPTGS2P2RX3KDM4E | |
| SCHEMBL8561030 | 0.84 | MAPT (0.56) | MAPTSMN1; SMN2NPC1KDM4E | |
| Hydrochloric Acid SCHEMBL8625846 | 0.83 | MAPT (0.55) | MAPTSMN1; SMN2NPC1KDM4E | |
| SCHEMBL8560369 | 0.83 | MAPT (0.44) | MAPTSMN1; SMN2NPC1KDM4E | |
| SCHEMBL8323681 | 0.83 | MAPT (0.49) | MAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL8330063 | 0.83 | DHODH (0.43) | MAPTDHODHP2RX3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |