SCHEMBL8324017

SCHEMBL8324017

CO/N=C1/CC(CC(=O)OC)N(C(=O)c2ccc(-c3ccccc3)cc2)C1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
OXTR P30559 5/20 0.64
AVPR1A P37288 3/20 0.64
POLB P06746 3/20 0.40
GAA P10253 1/20 0.40
ALDH1A1 P00352 3/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TRPV1 Q8NER1 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
BCL2 P10415 1/20 0.37
BAD Q92934 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13789902 1.00 OXTR (0.64) OXTRAVPR1APOLBGAAALDH1A1
SCHEMBL4416652 0.91 OXTR (0.67) OXTRAVPR1APOLBALDH1A1MEN1
SCHEMBL4416654 0.91 OXTR (0.67) OXTRAVPR1APOLBALDH1A1MEN1
SCHEMBL8314834 0.91 OXTR (0.67) OXTRAVPR1APOLBALDH1A1MEN1
SCHEMBL13789770 0.90 OXTR (0.61) OXTRAVPR1APOLBALDH1A1TRPV1
SCHEMBL4415819 0.90 OXTR (0.61) OXTRAVPR1APOLBALDH1A1TRPV1
SCHEMBL4415821 0.90 OXTR (0.61) OXTRAVPR1APOLBALDH1A1TRPV1
SCHEMBL13789776 0.89 OXTR (0.64) OXTRAVPR1APOLBALDH1A1MEN1
SCHEMBL4416684 0.89 OXTR (0.64) OXTRAVPR1APOLBALDH1A1MEN1
SCHEMBL4419417 0.89 OXTR (0.64) OXTRAVPR1APOLBALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004076407-A2 PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) 2004-09-10 WO disclosed